DI AND TRIVALENT IONS CO-SUBSTITUTED HYDROXYAPATITE NANOPARTICLES: SYNTHESIS, CHARACTERIZATION, ANTIBACTERIAL ACTIVITY AND IN VITRO STUDIES
Abstract
The present work is aimed at the synthesis of antibacterial and bioactive both divalent and trivalent substituted hydroxyapatite (LaMCa3(PO4)3OH, La0.7M0.3 Ca4(PO4)3OH (M = Sr, Zn, Mg) ) were synthesized by ultra sonic method. The as-synthesized samples were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), energy dispersive X-ray analysis (EDAX), high resolution transmission electron microscopy (HRTEM) and thermo gravimetric analysis (TGA). The antibacterial activity of the as-synthesized nanoparticles was evaluated against two prokaryotic strains (Escherichia coli and Staphylococcus aureus).